Polynucleotides
What are Polynucleotides at Inner Glow Aesthetics?
At Inner Glow Aesthetics, we offer advanced Polynucleotide treatments, a revolutionary category of regenerative injectables designed to rejuvenate skin at a cellular level. Polynucleotides are long-chain DNA fragments, typically derived from salmon or trout, that act as powerful biological messengers. Our expert practitioners administer them via micro-injections into the mesoderm (middle layer of the skin) to signal a powerful reparative response, stimulating your skin’s own healing mechanisms for comprehensive regeneration.
Treatment Duration & Frequency at Our Clinic: Your bespoke polynucleotide session at our clinic is a relaxing experience, typically lasting 30-45 minutes. For optimal regenerative results, we recommend an initial course of 3 sessions, spaced 3-4 weeks apart. To maintain the rejuvenated quality and resilience of your skin, we suggest periodic maintenance treatments, often 1-2 sessions per year.
How Long the Results Last: Results are progressive and cumulative, building with each session. You will notice improved hydration and luminosity after the first treatment, with significant improvements in skin density, texture, and tone becoming most apparent after the full course. As polynucleotides work by fundamentally improving your skin's health and function, results can be long-lasting, typically maintained for 9-12 months with a proper aftercare and maintenance plan.
Downtime & Aftercare: Polynucleotide treatments involve minimal downtime. Common post-treatment effects include mild redness, swelling, and sometimes minor bruising at the injection sites, which usually subside within 24-48 hours. We provide a clear, simple aftercare plan: avoid touching the area, excessive heat (sun, saunas), and strenuous exercise for 48 hours. Our team will give you comprehensive guidance to support your skin's healing process and maximise your regenerative results.
Main Benefits of Polynucleotide Treatments
Polynucleotide treatments deliver multi-faceted rejuvenation by addressing skin health from within. The key benefits include:
Powerful Skin Regeneration: Stimulates fibroblasts to boost the natural production of collagen, elastin, and hyaluronic acid for structural rebuilding.
Intense Hydration & Improved Barrier Function: Attracts and binds moisture while reinforcing the skin's protective lipid barrier for lasting hydration.
Enhanced Skin Density & Thickness: Counteracts age-related thinning by increasing dermal volume and improving overall skin firmness.
Reduction of Inflammation & Redness: Possesses natural anti-inflammatory properties, making it excellent for calming sensitive, rosacea-prone, or stressed skin.
Improved Skin Texture & Scar Remodelling: Promotes organised tissue repair, effectively smoothing fine lines, refining pores, and improving the appearance of scars (including acne and stretch marks).
Radiant, Unified Complexion: Restores skin vitality, leading to a noticeable glow, more even skin tone, and a revitalised appearance.
Who are Polynucleotide Treatments For?
Polynucleotide treatments are ideal for adults seeking preventative anti-ageing or comprehensive skin rejuvenation without synthetic fillers. They are perfect for individuals with skin that appears tired, dull, or thin, those with early signs of ageing and loss of elasticity, and anyone wishing to improve skin quality, resilience, and hydration on a cellular level. It is also a superb choice for those with sensitive skin, redness, or concerns with scarring or textural irregularities, and for clients who prefer a biostimulatory, "skin-remodelling" approach with natural, cumulative results.
Safty & Quality
All injectables are sourced from regulated suppliers and administered by certified clinicians following strict safety protocols.
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Yes. Polynucleotides are highly biocompatible and bio-stimulatory, meaning they are well-tolerated by the body and work with your own biology. Sourced from controlled, sustainable fisheries and subjected to rigorous purification and sterilisation processes, they have an excellent safety profile. As with all injectables, safety is ensured by choosing an experienced, medically-qualified practitioner.
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Discomfort is minimal. A topical numbing cream is applied beforehand to ensure comfort. The treatment involves a series of quick, superficial micro-injections using a very fine needle, which most clients describe as a mild, tolerable sensation.eedle. Sensation varies between individuals, but discomfort is generally minimal.
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You may notice an initial "glow" and improved hydration within the first week. However, as polynucleotides work by stimulating your skin's own regenerative processes, the most significant results develop progressively. Visible improvements in firmness, texture, and tone typically become more pronounced 4-6 weeks after each session, with the full benefits of a treatment course evident a few months after the final session.
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There is minimal social downtime. You can expect some temporary redness, slight swelling, and possibly minor bruising, similar to a light sunburn, which generally fades within 1-3 days. Most clients feel comfortable returning to normal activities the following day.
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To support healing and optimize results, we advise for the first 48 hours:
Avoid: Touching or rubbing the area, applying makeup (for 12 hours), intense heat (sun exposure, saunas, hot baths), and strenuous exercise.
Do: Keep the skin clean, apply any recommended healing ointments as advised, and use a high-factor sunscreen daily.
Gently pat the skin dry and avoid using active skincare (like retinols or acids) for 3-5 days post-treatment. Full, personalized aftercare instructions will be provided after your session.